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🔬 Comprehensive Nutrient & Supplement Rules Engine

This document details every specific rule, threshold, and logic gate used by the Nutrient Analytics algorithm. By consulting this guide, you can see exactly how and why a supplement or nutrient avoidance is recommended to a user without needing to inspect the software’s codebase.

1. The 4-Tier Priority Architecture

The system evaluates the user’s clinical profile top-down. If a conflict occurs, the lower tier recommendation is either modified or completely stripped (vetoed) by the higher tier.

  • Tier 1: Clinical Biomarkers. Hard medical data (bloodwork). Overrides all other tiers.
  • Tier 2: Systemic Risks. Assessed clinical conditions (Gut health, Metabolic status, Sleep disorders).
  • Tier 3: Mind & Nervous System. Mental health baselines (Burnout, Anxiety, Stress).
  • Tier 4: Performance & Body Objectives. User goals (Weight loss, Muscle gain). Lowest priority.

2. Tier 1: Clinical Biomarkers (Bloodwork) Ruleset

These recommendations are triggered explicitly by uploaded lab results falling outside optimal ranges.

Biomarker Threshold Action Nutrient / Supplement System Rationale
Vitamin D < 75 Adopt Vitamin D3 & K2 Levels are suboptimal. K2 helps safely direct calcium to your bones.
Ferritin < 50 Adopt Heme Iron & Vitamin C Iron stores need a boost. Vitamin C naturally increases absorption.
B12 < 400
OR Folate < 15
Adopt Methylated B12 & Folate Crucial support for cellular energy, brain function, and methylation.
HbA1c > 41 Avoid
Adopt
Refined Sugars & HFCS
Berberine or Alpha Lipoic Acid
Limits blood sugar spikes. Berberine supports cellular insulin sensitivity.
Triglycerides > 1.7 Avoid Excess Fructose & Trans Fats Reducing these helps balance blood lipid profiles naturally.
LDL > 3.5 Adopt
Avoid
Soluble Fiber (Beta-Glucans)
Excess Saturated Fats
Fiber binds to cholesterol to excrete it; limiting saturated fat supports heart health.
HDL < 1.0 Adopt Omega-3 (EPA/DHA) & Olive Oil Healthy fats that naturally support the increase of protective HDL.
ALT > 40
OR GGT > 40
Avoid
Adopt
Alcohol & Processed Oils
Choline & Milk Thistle
Removes liver stress; supplements provide raw materials to clear fat deposits.
CRP > 3.0 Adopt
Avoid
Curcumin & Omega-3
Ultra-Processed Foods
Powerful natural anti-inflammatories to cool systemic stress.
Creatinine > 100
OR eGFR < 60
Avoid
[VETO]
Excessive Protein (>1.5g/kg) Reduces filtration burden on kidneys. Generates the KidneyStress internal veto flag.
TSH > 4.5
OR FT4 < 12
Adopt
Avoid
Iodine, Selenium & Zinc
Raw Goitrogens (Raw Kale/Broccoli)
Building blocks for thyroid hormones. Raw cruciferous veg blocks iodine uptake.
Testosterone < 12
(Males Only)
Adopt Zinc, Magnesium & Vitamin D Foundational micronutrients required for natural testosterone synthesis.

3. Tier 2: Systemic Risks Ruleset

Triggered by assessments of digestive, metabolic, and sleep health.

Condition Threshold Action Nutrient / Supplement System Rationale
Lactose (Severe/High) Avoid
Adopt
[VETO]
Lactose & Dairy
Plant-based Calcium
Reduces inflammation. Generates the Whey internal veto flag.
Celiac (Severe/High) Avoid
Adopt
Gluten, Wheat, Barley, Rye
L-Glutamine & Bone Broth
Protects intestinal health. Glutamine soothes the gut lining and supports repair.
IBS or SIBO (Severe) Avoid
Adopt
High FODMAPs & Sugar Alcohols
Peppermint Oil & PHGG Fiber
Limits fermentation and bloating. Peppermint soothes the digestive tract.
High Blood Pressure (Yes) Adopt
Avoid
Adopt
Potassium-Rich Foods
High Dietary Sodium & Licorice
Dietary Nitrates (Beetroot)
Potassium/Nitrates act as vasodilators to relax blood vessels and excrete sodium.
Visceral Fat (High/Severe) Avoid
Adopt
Liquid Fructose (Sodas/Juice)
Green Tea Extract (EGCG)
Fructose converts to belly fat. EGCG supports abdominal fat oxidation.
Diabetes (High/Severe) Avoid
Adopt
High GI Carbohydrates
Chromium & Ceylon Cinnamon
Limits simple sugars for steady energy; supplements healthy blood sugar metabolism.
Insomnia (High/Severe) Avoid
Adopt
Post-12PM Caffeine & Alcohol
Magnesium Bisglycinate & Apigenin
Alcohol destroys REM. Magnesium/Apigenin calms the central nervous system.
Circadian (High/Severe) Adopt
Avoid
Melatonin-Rich Foods (Tart Cherry)
Heavy Meals within 3 Hrs of Bed
Encourages sleep window onset. Late digestion increases core body temperature.

4. Tier 3: Mind & Nervous System Ruleset

Triggered by the user’s current psychological and emotional state.

Psychological State Action Nutrient / Supplement System Rationale
Burnout / Freeze State Avoid
Adopt
High-Dose Stimulants
Adaptogens (Ashwagandha/Rhodiola)
Allows exhausted nervous system to recover. Adaptogens gently process stress.
GAD Anxiety (High/Severe) Adopt
Avoid
L-Theanine
Excessive Caffeine
Theanine promotes calm focus. Caffeine mimics physiological panic response.

5. Tier 4: Performance & Body Objectives Ruleset

Triggered purely by the user’s stated fitness goals, subject to vetoes from higher tiers.

Objective Action Nutrient / Supplement System Rationale
Build Muscle Adopt High-Quality Whey Protein
(Swaps to Plant/Beef Isolate if Whey Veto is active)
Provides essential amino acids for lean muscle synthesis.
Build Muscle Adopt Creatine Monohydrate
(Deleted entirely if KidneyStress Veto is active)
Supports strength and cellular energy.
Weight Loss Avoid
Adopt
Liquid Calories & Hidden Sugars
High-Volume Soluble Fiber
Ensures fuel comes from satiating foods. Fiber promotes fullness.
Weight Gain Adopt Caloric-Dense Healthy Fats Provides clean, easily digestible calories to reach a surplus.
High Daily Activity
(Burn > 500 kcal/day)
Adopt Electrolytes (Na, K, Mg) Replenishes vital minerals lost through high physical exertion.

6. The Internal Veto System (Safeguards)

The system actively prevents conflicting advice using silent tracking tags known as Vetoes.

The [Whey] Veto
If the user flags as having High/Severe Lactose intolerance in Tier 2, the system engages the [Whey] veto. When the system reaches Tier 4 and attempts to recommend Whey Protein for muscle building, the veto catches it and automatically substitutes the recommendation for “Plant/Beef Isolate Protein”.
The[KidneyStress] Veto
If the user has High Creatinine or Low eGFR in their Tier 1 bloodwork, the system engages the [KidneyStress] veto. When the system reaches Tier 4 and attempts to recommend Creatine Monohydrate for muscle building, the veto deletes the recommendation entirely, as Creatine can falsely elevate blood creatinine and burden compromised kidneys.